SCHEMBL4354860

SCHEMBL4354860

c1ccc2nc(C3CNCCO3)ccc2c1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.46
DRD3 P35462 1/20 0.46
HRH1 P35367 3/20 0.45
KCNH2 Q12809 3/20 0.45
CYP2D6 P10635 2/20 0.45
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27902231 1.00 DRD2 (0.46) DRD2DRD3HRH1KCNH2CYP2D6
SCHEMBL28156000 0.81 HRH1 (0.44) HRH1KCNH2CYP2D6
SCHEMBL32674522 0.80 RAB9A (0.46) CYP2D6CYP3A4
SCHEMBL27932853 0.80 DRD2 (0.42) DRD2DRD3
SCHEMBL27996919 0.78 DRD2 (0.49) DRD2DRD3HRH1KCNH2CYP2D6
SCHEMBL1582896 0.77 RAB9A (0.49) CYP2D6CYP3A4
SCHEMBL22576041 0.77 DRD2 (0.40) DRD2DRD3
SCHEMBL14481220 0.77 HRH1 (0.44) DRD2DRD3HRH1KCNH2CYP2D6
SCHEMBL28657514 0.76 HTT (0.45) CYP2D6CYP3A4
SCHEMBL12609780 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108794411-A Certain chemical entities, composition and method 润新生物公司 2018-11-13 CN disclosed
CN-104053442-B Certain chemical entities, compositions, and methods 润新生物公司 2017-06-23 CN disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
CN-1295523-C Optical filter FUJI PHOTO FILM CO LTD (JP) 2007-01-17 CN disclosed
US-6911238-B2 Liquid crystal compositions, polarization selective membranes and liquid crystal displays FUJI PHOTO FILM CO., LTD. (JP) 2005-06-28 US disclosed
US-20030218715-A1 Liquid crystal compositions, polarization selective membranes and liquid crystal displays FUJI PHOTO FILM CO., LTD. 2003-11-27 US disclosed
US-6586057-B1 Filter layer contains a dye and a binder polymer. The dye is in a non-aggregated form. The dye has an absorption maximum with a half width of not more than 100 nm within the wavelength region of 560 to 620 nm. The transparent support, FUJI PHOTO FILM CO., LTD. (JP) 2003-07-01 US disclosed
US-6532120-B1 Correcting color appropriately for a displayed image; absorbs undesired light component emitted from an image display (especially, a plasma display panel); a dye and a binder polymer; maximum wavelength region of 560 to 620 nm FUJI PHOTO FILM CO., LTD. (JP) 2003-03-11 US disclosed
CN-1331806-A Optical filter FUJI PHOTO FILM CO LTD (JP) 2002-01-16 CN disclosed
EP-1124144-A1 OPTICAL FILTER FUJI PHOTO FILM CO., LTD. (JP) 2001-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274853-A1 DICHROIC DYE COMPOSITION C1S, CDY1; CDY1B, CRY1 DRD2 247/4885DRD3 142/4885HRH1 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.