Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722580 | 0.89 | PLK1 (0.42) | KMT2AMEN1TP53ALDH1A1HCAR3 | |
| SCHEMBL28062163 | 0.86 | KMT2A (0.53) | KMT2AMEN1TP53RAB9ANPC1 | |
| SCHEMBL1875530 | 0.84 | CRHBP (0.52) | GAAALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL1875534 | 0.84 | CRHBP (0.52) | GAAALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL7059267 | 0.82 | HCAR3 (0.43) | GAAALDH1A1MAPTHCAR3 | |
| SCHEMBL5582439 | 0.82 | MEN1 (0.54) | KMT2AMEN1RAB9ANPC1NPSR1 | |
| SCHEMBL5582440 | 0.82 | MEN1 (0.54) | KMT2AMEN1RAB9ANPC1NPSR1 | |
| SCHEMBL5582438 | 0.82 | MEN1 (0.54) | KMT2AMEN1RAB9ANPC1NPSR1 | |
| SCHEMBL22496020 | 0.82 | CYP1A2 (0.45) | KMT2AMEN1RAB9ANPC1NPSR1 | |
| SCHEMBL20840359 | 0.82 | ALDH1A1 (0.51) | KMT2AMEN1TP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085067-A2 | BOUNDARY CONDITIONS FOR THE ARRANGEMENT OF CELLS AND TISSUES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-07-09 | — | — | WO | disclosed |
| CN-1113389-A | High molecular weight desulphatohirudin | CIBA GEIGY AG (CH) | 1995-12-13 | — | — | CN | disclosed |