Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301799 | 0.82 | CYP2C19 (0.43) | ALDH1A1CYP2C19ALOX12KMT2AL3MBTL1 | |
| SCHEMBL4295091 | 0.79 | HDAC8 (0.38) | GAAALDH1A1EPHX1HTT | |
| SCHEMBL1875535 | 0.77 | KMT2A (0.35) | GAAALDH1A1NPSR1CYP2C19HTT | |
| SCHEMBL10765101 | 0.75 | GAA (0.48) | GAAALDH1A1NPSR1EPHX1CYP2C19 | |
| SCHEMBL7768186 | 0.74 | GAA (0.50) | GAAALDH1A1NPSR1EPHX1CYP2C19 | |
| SCHEMBL10687645 | 0.72 | MAPT (0.49) | GAAALDH1A1HTTALOX12KMT2A | |
| SCHEMBL3969392 | 0.72 | KIF11 (0.42) | GAAALDH1A1CYP2C19HTTKMT2A | |
| SCHEMBL5025929 | 0.72 | SMN1; SMN2 (0.41) | GAAALDH1A1NPSR1EPHX1ALOX12 | |
| SCHEMBL5513747 | 0.71 | GAA (0.54) | GAAALDH1A1NPSR1EPHX1CYP2C19 | |
| SCHEMBL28866511 | 0.70 | CES1 (0.44) | GAAALDH1A1MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085067-A2 | BOUNDARY CONDITIONS FOR THE ARRANGEMENT OF CELLS AND TISSUES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-07-09 | — | — | WO | disclosed |