Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6821751 | 0.98 | HPGDS (0.71) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL26319518 | 0.96 | ALDH1A1 (0.73) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL27768678 | 0.89 | HDAC1 (0.70) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL657641 | 0.87 | ALDH1A1 (0.70) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL7776324 | 0.87 | ALDH1A1 (0.65) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL2311294 | 0.85 | HPGDS (1.00) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL168519 | 0.85 | HTR2B (0.66) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL2104811 | 0.85 | ALDH1A1 (0.73) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL1574742 | 0.85 | HDAC1 (0.66) | HPGDSALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL1785557 | 0.85 | ALDH1A1 (0.73) | HPGDSALDH1A1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108546225-B | Process for producing nitrile and corresponding amine | 中国石化扬子石油化工有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-111892532-A | Method for synthesizing 3-Cl propionyl substituted heterocyclic compound containing N by using micro-reaction device | 南京工业大学 | 2020-11-06 | — | — | CN | claimed |
| CN-108546225-A | The manufacturing method of nitrile and its corresponding amine | 中国石化扬子石油化工有限公司 | 2018-09-18 | — | — | CN | claimed |
| CN-104557357-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2018-04-27 | — | — | CN | claimed |
| CN-104557357-A | Process for the manufacture of nitriles and their corresponding amines | SINOPEC YANGZI PETROCHEMICAL | 2015-04-29 | — | — | CN | claimed |
| CN-101384544-B | Substituted cyclohexylmethyl derivatives | GRUENENTHAL GMBH | 2014-01-22 | — | — | CN | claimed |
| US-8058475-B2 | Substituted cyclohexylmethyl compounds | GRUENENTHAL GMBH (DE) | 2011-11-15 | — | — | US | claimed |
| EP-1989174-B1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-08-03 | — | — | EP | claimed |
| CN-101835757-A | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE | 2010-09-15 | — | — | CN | claimed |
| EP-2155687-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2010-02-24 | — | — | EP | claimed |
| CN-101384544-A | Substituted cyclohexylmethyl derivatives | GRUENENTHAL GMBH (DE) | 2009-03-11 | — | — | CN | claimed |
| CN-101370796-A | Thiazoles as 11 beta-HSD1 inhibitors | HOFFMANN LA ROCHE (CH) | 2009-02-18 | — | — | CN | claimed |
| CN-101316844-A | Inhibitors of diacylglycerol acyltransferase (DGAT) | HOFFMANN LA ROCHE (CH) | 2008-12-03 | — | — | CN | claimed |
| WO-2008141976-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | claimed |
| EP-1979335-A2 | THIAZOLES AS 11 BETA-HSD1 INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-10-15 | — | — | EP | claimed |
| US-20080242671-A1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2008-10-02 | — | — | US | claimed |
| EP-1963313-A2 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE (DGAT) | F.HOFFMANN-LA ROCHE AG (CH) | 2008-09-03 | — | — | EP | claimed |
| WO-2007082808-A2 | THIAZOLES AS 11 BETA-HSD1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-07-26 | — | — | WO | claimed |
| WO-2007060140-A2 | INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE (DGAT) | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-31 | — | — | WO | claimed |
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242671-A1 | INHIBITORS OF CATHEPSIN S | CTSS, CTSB, CTSZ | HPGDS 615/4885ALDH1A1 3512/4885HDAC1 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.