Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038139 | 0.95 | TSHR (0.51) | TSHRALDH1A1TDP1POLBAPEX1 | |
| SCHEMBL4162825 | 0.95 | TSHR (0.51) | TSHRALDH1A1TDP1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL5015842 | 0.94 | TSHR (0.50) | TSHRALDH1A1TDP1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL11323572 | 0.94 | TSHR (0.50) | TSHRALDH1A1TDP1POLBAPEX1 | |
| SCHEMBL3185598 | 0.92 | TSHR (0.48) | TSHRALDH1A1TDP1POLBAPEX1 | |
| SCHEMBL1403009 | 0.87 | ALDH1A1 (0.47) | TSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL6664042 | 0.85 | TSHR (0.48) | TSHRALDH1A1TDP1POLBAPEX1 | |
| SCHEMBL4165361 | 0.85 | TSHR (0.48) | TSHRALDH1A1TDP1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL2580360 | 0.85 | TSHR (0.54) | TSHRALDH1A1TDP1POLBAPEX1 | |
| SCHEMBL29664602 | 0.85 | THRB (0.39) | TSHRALDH1A1TDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285891-A1 | Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and method for its production | DR. R. PFLEGER CHEMISCHE FABRIK GMBH (DE) | 2009-11-19 | — | — | US | claimed |
| US-8221787-B2 | Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and method for its production | Dr. Robert Pfleger Chemische Fabrik GmbH (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20090285891-A1 | Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and method for its production | DR. R. PFLEGER CHEMISCHE FABRIK GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| CN-1330305-C | Highly flexible transdermal therapeutic system having nicotine as active substance | LOHMANN THERAPIE SYST LTS (DE) | 2007-08-08 | — | — | CN | disclosed |
| CN-1494421-A | High-flexibility transdermal therapeutic system comprising nicotine as active ingredient | LTS��������ϵͳ�ɷݹ�˾ | 2004-05-05 | — | — | CN | disclosed |