Methacrylic Acid

Methacrylic Acid

SCHEMBL2580360

C=C(C)C(=O)O.C=C(C)C(=O)OC.C=C(C)C(=O)OCCCC.C=C(C)C(=O)OCCN(C)C

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
DNM1 Q05193 1/20 0.43
ALDH1A1 P00352 4/20 0.42
THRB P10828 1/20 0.41
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.38
MAOA P21397 1/20 0.38
CNR1 P21554 1/20 0.38
DRD4 P21917 1/20 0.38
ACHE P22303 1/20 0.38
HRH2 P25021 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
MAPK1 P28482 1/20 0.38
NTSR1 P30989 1/20 0.38
HRH1 P35367 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427500 0.96 TSHR (0.58) TSHRDNM1ALDH1A1THRBPOLB
Hydrochloric Acid SCHEMBL25265974 0.94 TSHR (0.57) TSHRDNM1ALDH1A1THRBPOLB
Methacrylic Acid SCHEMBL4638039 0.91 ALDH1A1 (0.50) TSHRDNM1ALDH1A1THRBPOLB
SCHEMBL9767545 0.90 TSHR (0.69) TSHRDNM1ALDH1A1THRBPOLB
SCHEMBL3366486 0.90 TSHR (0.69) TSHRDNM1ALDH1A1THRBPOLB
SCHEMBL8424369 0.90 TSHR (0.66) TSHRDNM1ALDH1A1THRBPOLB
SCHEMBL1704602 0.90 TSHR (0.66) TSHRDNM1ALDH1A1THRBPOLB
Methacrylic Acid SCHEMBL27388646 0.90 TSHR (0.66) TSHRALDH1A1THRBPOLBAPEX1
Methacrylic Acid SCHEMBL4865839 0.90 TSHR (0.66) TSHRALDH1A1THRBPOLBAPEX1
Cadaverine Tartrate SCHEMBL25213297 0.90 TSHR (0.49) TSHRDNM1ALDH1A1THRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4241758-A2 ANTI-DANDRUFF COMPOSITION L'OREAL (FR) 2023-09-13 EP disclosed
EP-2934454-B1 ANTI-DANDRUFF COMPOSITION OREAL (FR) 2023-07-12 EP disclosed
US-11000470-B2 Methods, compositions, and kits for treating hair L'OREAL (FR) 2021-05-11 US disclosed
US-20190029948-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING HAIR L'OREAL (FR) 2019-01-31 US disclosed
EP-2934454-A1 ANTI-DANDRUFF COMPOSITION L'Oréal (FR) 2015-10-28 EP disclosed
US-8920787-B2 Mascara containing an aqueous dispersion of polyurethane and an acrylic film former L'OREAL (FR) 2014-12-30 US disclosed
US-8846018-B2 Mascara compositions containing at least two acrylate film formers L'OREAL (FR) 2014-09-30 US disclosed
WO-2014095625-A1 ANTI-DANDRUFF COMPOSITION L'OREAL (FR) 2014-06-26 WO disclosed
US-8574561-B1 Compositions containing anti-dandruff agents L'OREAL (FR) 2013-11-05 US disclosed
EP-2563326-A2 MASCARA CONTAINING AN AQUEOUS DISPERSION OF POLYURETHANE AND AN ACRYLIC FILM FORMER L'Oréal SA (FR) 2013-03-06 EP disclosed
US-20130039874-A1 MASCARA CONTAINING AN AQUEOUS DISPERSION OF POLYURETHANE AND AN ACRYLIC FILM FORMER L'OREAL S.A. (FR) 2013-02-14 US disclosed
US-20130028650-A1 MASCARA COMPOSITIONS CONTAINING AT LEAST TWO ACRYLATE FILM FORMERS L'OREAL (FR) 2013-01-31 US disclosed
US-20110300092-A1 MASCARAS OBTAINED VIA MULTI-PHASE PRODUCT L'OREAL (FR) 2011-12-08 US disclosed
WO-2011137338-A2 MASCARA CONTAINING AN AQUEOUS DISPERSION OF POLYURETHANE AND AN ACRYLIC FILM FORMER L'OREAL S.A. (FR) 2011-11-03 WO disclosed
CN-101926743-A Mineral-oil free, polymerically stabilized make-up remover OREAL 2010-12-29 CN disclosed
US-20100137179-A1 Mineral oil free polymerically stabilized make-up remover L'OREAL (FR) 2010-06-03 US disclosed
EP-2181695-A2 Mineral-oil free, polymerically stabilized make-up remover L'Oreal (FR) 2010-05-05 EP disclosed
US-20100028284-A1 Mascara compositions containing at least two acrylate film formers L'OREAL (FR) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130039874-A1 MASCARA CONTAINING AN AQUEOUS DISPERSION OF POLYURETHANE AND AN ACRYLIC FILM FORMER ALG3, SMC3, MATR3 TSHR 4810/4885DNM1 708/4885ALDH1A1 844/4885
US-11000470-B2 Methods, compositions, and kits for treating hair CBL, FZD7, EZH2 TSHR 2133/4885DNM1 4163/4885ALDH1A1 3915/4885
US-20100137179-A1 Mineral oil free polymerically stabilized make-up remover DEGS1, CUTA, SMURF1 TSHR 2164/4885DNM1 3021/4885ALDH1A1 4658/4885
US-20110300092-A1 MASCARAS OBTAINED VIA MULTI-PHASE PRODUCT CUTA, AQP3, LSS TSHR 3462/4885DNM1 2393/4885ALDH1A1 2122/4885
US-20190029948-A1 METHODS, COMPOSITIONS, AND KITS FOR TREATING HAIR CBL, FZD7, EZH2 TSHR 2133/4885DNM1 4163/4885ALDH1A1 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.