Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355963 | 0.86 | TDP1 (0.64) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL10109430 | 0.86 | TDP1 (0.64) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL500245 | 0.85 | TDP1 (0.43) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL9742159 | 0.78 | ALDH1A1 (0.75) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL31190867 | 0.72 | ALDH1A1 (0.52) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL31190871 | 0.71 | TSHR (0.51) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL13827600 | 0.69 | HTT (0.45) | TSHRALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11436041 | 0.69 | NPSR1 (0.48) | TDP1HSD17B10 | |
| SCHEMBL29414050 | 0.69 | NPSR1 (0.48) | TDP1HSD17B10 | |
| SCHEMBL13598792 | 0.67 | ALDH1A1 (0.68) | TDP1TSHRALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014037202-A2 | PESTICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-03-13 | — | — | WO | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012143395-A1 | 4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |