SCHEMBL500245

SCHEMBL500245

CCCc1nc(C)cc(OP(O)(O)=S)n1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
ACHE P22303 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTT P42858 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.31
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435631 0.85 TDP1 (0.48) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL29355963 0.82 TDP1 (0.64) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL10109430 0.82 TDP1 (0.64) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL1901390 0.77 TDP1 (0.70) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL13827600 0.73 HTT (0.45) ALDH1A1TSHRHTTLMNAMAPT
SCHEMBL29414050 0.73 NPSR1 (0.48) TDP1HSD17B10HTTHCRTR1HCRTR2
SCHEMBL11436041 0.73 NPSR1 (0.48) TDP1HSD17B10HTTHCRTR1HCRTR2
SCHEMBL3726052 0.72 TDP1 (0.49) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL988426 0.71 ALDH1A1 (0.64) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL10493507 0.71 ALDH1A1 (0.36) TDP1ALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2347655-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngenta Participations AG. (CH) 2011-07-27 EP claimed
EP-2332411-A1 Fungicidal compositions Syngenta Participations AG (CH) 2011-06-15 EP claimed
JP-2008509189-A 2008-03-27 JP claimed
US-20080076664-A1 Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. 2008-03-27 US claimed
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic SYNGENTA CROP PROTECTION, INC. (US) 2008-03-20 US claimed
EP-1778013-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-05-02 EP claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 WO claimed
US-20240208962-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 US disclosed
WO-2024132901-A1 MICROBIOCIDAL PYRIDAZINE DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
WO-2024132895-A1 MICROBIOCIDAL DIHYDROOXADIAZINYL PYRIDAZINONE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
WO-2024126407-A1 BENZIMIDAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
WO-2024126404-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
WO-2024126650-A1 NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 WO disclosed
US-20060166898-A1 Fertilizer-compatible composition BAYER CROPSCIENCE LP 2006-07-27 US disclosed
WO-2006061200-A1 ANTHRANILAMIDE DERIVATIVES AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2006-06-15 WO disclosed
WO-2006037632-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO disclosed
US-20050274059-A1 Pesticidal mixtures SYNGENTA CROP PROTECTION, INC. 2005-12-15 US disclosed
WO-2005107468-A1 PESTICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2005-11-17 WO disclosed
EP-1315421-B1 ORGANOPHOSPHOROUS COMPOSITIONS BASF CORP (US) 2004-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208962-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES IFNG, IRF3, MAVS TDP1 1041/4885ALDH1A1 1076/4885TP53 2094/4885
US-20060166898-A1 Fertilizer-compatible composition MYB, PPA1, GFPT1 TDP1 1925/4885ALDH1A1 4094/4885TP53 2984/4885
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic BROX, EPM2A, MANBA TDP1 2299/4885ALDH1A1 4291/4885TP53 3380/4885
US-20080076664-A1 Fungicidal Compositions AKR7A2, CYP51A1, TUBA3C TDP1 966/4885ALDH1A1 1173/4885TP53 4397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.