Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355963 | 1.00 | TDP1 (0.64) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL435631 | 0.86 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL31190867 | 0.82 | ALDH1A1 (0.52) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL500245 | 0.82 | TDP1 (0.43) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL13598792 | 0.81 | ALDH1A1 (0.68) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL31190871 | 0.81 | TSHR (0.51) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| Pirimiphos-Ethyl SCHEMBL7869678 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| Pirimiphos-Ethyl SCHEMBL29413995 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| Pirimiphos-Ethyl SCHEMBL74180 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL29721170 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024068947-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024068950-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-04-04 | — | — | WO | disclosed |
| EP-4312556-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-02-07 | — | — | EP | disclosed |
| US-10544148-B2 | Pesticidally active tetracyclic heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-28 | — | — | US | disclosed |
| US-20170240554-A1 | PESTICIDALLY ACTIVE TETRACYCLIC HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-24 | — | — | US | disclosed |
| US-8846567-B2 | Active compound combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| CN-104024225-A | Pesticidal compounds | SYNGENTA PARTICIPATIONS AG | 2014-09-03 | — | — | CN | disclosed |
| CN-104011024-A | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG | 2014-08-27 | — | — | CN | disclosed |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544148-B2 | Pesticidally active tetracyclic heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, TST | TDP1 1748/4885ALDH1A1 433/4885TSHR 554/4885 |
| US-20170240554-A1 | PESTICIDALLY ACTIVE TETRACYCLIC HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, TST | TDP1 1748/4885ALDH1A1 433/4885TSHR 554/4885 |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | ACHE, DDT, BCHE | TDP1 2269/4885ALDH1A1 424/4885TSHR 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.