Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
| ▸ | INSR | P06213 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344137 | 0.99 | BRD4 (0.43) | BRD4CAMKK2CHUKINSRMAPK8 | |
| SCHEMBL4351733 | 0.91 | BRD4 (0.41) | BRD4CAMKK2CHUKINSRMAPK8 | |
| SCHEMBL4340973 | 0.86 | BRD4 (0.41) | BRD4CAMKK2CHUKINSRMAPK8 | |
| SCHEMBL13685462 | 0.82 | BRD4 (0.47) | BRD4CAMKK2CHUKINSRMAPK8 | |
| SCHEMBL4339928 | 0.79 | CCNT1 (0.37) | BRD4ALDH1A1HPGD | |
| SCHEMBL4350108 | 0.79 | SLC9A1 (0.38) | BRD4ALDH1A1SMN1; SMN2MAP2NPC1 | |
| SCHEMBL2196927 | 0.78 | CDC7 (0.54) | BRD4CAMKK2CHUKINSRMAPK8 | |
| SCHEMBL2198991 | 0.78 | KDM4E (0.53) | CAMKK2CHUKINSRMAPK8ALDH1A1 | |
| SCHEMBL2201065 | 0.77 | KDM4E (0.51) | CAMKK2CHUKINSRMAPK8ALDH1A1 | |
| SCHEMBL2198565 | 0.76 | BRD4 (0.50) | BRD4CAMKK2CHUKINSRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116530-B1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |
| EP-2116530-A1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-11 | — | — | EP | disclosed |