Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 14/20 | 0.37 |
| ▸ | CDK9 | P50750 | 14/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195866 | 0.81 | ALDH1A1 (0.47) | CCNT1CDK9KDM4EALDH1A1 | |
| SCHEMBL4344137 | 0.80 | BRD4 (0.43) | BRD4ALDH1A1 | |
| SCHEMBL4357005 | 0.79 | BRD4 (0.42) | BRD4ALDH1A1HPGD | |
| SCHEMBL4344141 | 0.79 | BRD4 (0.41) | CCNT1CDK9BRD4ABL1 | |
| SCHEMBL4351733 | 0.79 | BRD4 (0.41) | BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL4350108 | 0.78 | SLC9A1 (0.38) | BRD4ALDH1A1 | |
| SCHEMBL2197511 | 0.77 | BRD4 (0.46) | CCNT1CDK9BRD4 | |
| SCHEMBL4344585 | 0.75 | BRD4 (0.45) | CCNT1CDK9BRD4ALDH1A1 | |
| SCHEMBL4344042 | 0.75 | BRD4 (0.38) | CCNT1CDK9BRD4HPGD | |
| SCHEMBL2196441 | 0.74 | BRD4 (0.44) | CCNT1CDK9BRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116530-B1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-14 | — | — | EP | claimed |
| EP-2116530-A1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-11 | — | — | EP | claimed |