SCHEMBL789811

SCHEMBL789811

Nc1ccc(Cl)cc1C=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.57
TDP1 Q9NUW8 2/20 0.56
TSHR P16473 4/20 0.52
CYP3A4 P08684 3/20 0.52
ALOX15 P16050 3/20 0.52
ALDH1A1 P00352 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TP53 P04637 1/20 0.44
HSD17B10 Q99714 2/20 0.41
ALOX12 P18054 2/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
PTPN1 P18031 1/20 0.41
RECQL P46063 1/20 0.39
NR4A2 P43354 1/20 0.38
XDH P47989 1/20 0.38
IDO1 P14902 1/20 0.38
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29956054 0.98 ERN1 (0.55) ERN1TDP1TSHRCYP3A4ALOX15
Bromide SCHEMBL29952083 0.98 ERN1 (0.55) ERN1TDP1TSHRCYP3A4ALOX15
Alcohol SCHEMBL28369215 0.89 ERN1 (0.52) ERN1TDP1TSHRCYP3A4ALOX15
SCHEMBL4357334 0.83 TDP1 (0.70) ERN1TDP1ALDH1A1SMN1; SMN2TP53
SCHEMBL3208051 0.82 TDP1 (0.61) ERN1TDP1TSHRCYP3A4ALOX15
Water SCHEMBL28578537 0.81 TDP1 (0.67) ERN1TDP1ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL24630268 0.77 CYP3A4 (0.52) ERN1TDP1TSHRCYP3A4ALOX15
SCHEMBL27472917 0.77 ALDH1A1 (0.52) ERN1TDP1TSHRCYP3A4ALOX15
SCHEMBL135290 0.76 TDP1 (0.40) ERN1TDP1TSHRCYP3A4ALOX15
SCHEMBL9404722 0.76 TDP1 (0.48) ERN1TDP1TSHRCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-12098132-B2 Process for preparation of aldehyde scavenger and intermediates ALDEYRA THERAPEUTICS, INC. (US) 2024-09-24 US claimed
CN-118046642-A Antioxidant composite fabric and preparation method thereof 柯乘武 2024-05-17 CN claimed
CN-115850240-B Synthesis method of medicine ao Lu Taxi Ni for treating acute myelogenous leukemia 北京康立生医药技术开发有限公司 2023-09-19 CN claimed
CN-115850240-A Synthetic method of drug Olutascinonide for treating acute myeloid leukemia 北京康立生医药技术开发有限公司 2023-03-28 CN claimed
US-20220089542-A1 PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES ALDEYRA THERAPEUTICS, INC. 2022-03-24 US claimed
WO-2020223717-A1 PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES ALDEYRA THERAPEUTICS, INC. (US) 2020-11-05 WO claimed
CN-107522766-B Ursolic acid quinolyl hydrazide derivatives with anti-tumor activity and preparation method and application thereof 南京林业大学 2020-03-27 CN claimed
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP claimed
US-20130190500-A1 PROCESS TO PREPARE 6-CHLORO-3-AMINO-2-(2-HYDROXYPROPYL)-1-AZANAPHTHALENE NEURON SYSTEMS, INC. (US) 2013-07-25 US claimed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN claimed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN claimed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP claimed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO claimed
US-20260132137-A1 SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF HOFFMANN LA ROCHE INC (US) 2026-05-14 US disclosed
CN-121871212-A Sound-absorbing electromagnetic wave-preventing glass and preparation method thereof 杭州恩隆科技有限公司 2026-04-17 CN disclosed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP disclosed
US-4981968-A ENZYME INHIBITORS, ANTITUMOR RESEARCH TRIANGLE INSTITUTE (US) 1991-01-01 US disclosed
WO-1990003169-A1 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF RESEARCH TRIANGLE INSTITUTE (US) 1990-04-05 WO disclosed
US-4894456-A CYCLIZATION, ESTERIFICATION RESEARCH TRIANGLE INSTITUTE (US) 1990-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089542-A1 PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES ALDH2, AOX1, ALDH1A1 ERN1 3145/4885TDP1 1562/4885TSHR 2958/4885
US-12098132-B2 Process for preparation of aldehyde scavenger and intermediates ALDH2, AOX1, ALDH1A1 ERN1 3145/4885TDP1 1562/4885TSHR 2958/4885
US-20130190500-A1 PROCESS TO PREPARE 6-CHLORO-3-AMINO-2-(2-HYDROXYPROPYL)-1-AZANAPHTHALENE AZI2, DNMT1, TPMT ERN1 4393/4885TDP1 1661/4885TSHR 3185/4885
US-20260132137-A1 SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF YWHAQ, CCT8, CYP2C18 ERN1 2515/4885TDP1 100/4885TSHR 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.