SCHEMBL95435

SCHEMBL95435

O=Cc1ccc(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 1.00
ERN1 O75460 3/20 0.56
TP53 P04637 1/20 0.48
MAPT P10636 4/20 0.47
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
GABRA1 P14867 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
IGF1R P08069 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29889164 1.00 TDP1 (1.00) TDP1ERN1TP53MAPTALDH1A1
Ammonia Solution, Strong SCHEMBL8037724 0.98 TDP1 (0.95) TDP1ERN1TP53MAPTALDH1A1
SCHEMBL8073452 0.83 TDP1 (0.69) TDP1ERN1TP53MAPTALDH1A1
SCHEMBL609449 0.82 TDP1 (0.69) TDP1ERN1MAPTALDH1A1KDM4E
SCHEMBL4357334 0.82 TDP1 (0.70) TDP1ERN1TP53MAPTALDH1A1
Cyclohexylamine SCHEMBL7798607 0.80 TDP1 (0.65) TDP1ERN1MAPTALDH1A1KDM4E
SCHEMBL7798353 0.80 TDP1 (0.65) TDP1ERN1MAPTALDH1A1KDM4E
Cycloheptanamine SCHEMBL7801564 0.80 TDP1 (0.65) TDP1ERN1MAPTALDH1A1KDM4E
Water SCHEMBL28578537 0.80 TDP1 (0.67) TDP1ERN1MAPTALDH1A1GABRA1
SCHEMBL11872397 0.80 TDP1 (0.67) TDP1ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4528 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606265-B Protocatechu derivative and synthesis method and application thereof 山西大学 2025-05-02 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-119371374-A Green synthesis method of 2-amino-5-aryl-1, 3, 4-thiadiazole 陕西科技大学 2025-01-28 CN claimed
CN-114891011-B Preparation method of medical intermediate 2-amino-tetrahydropyran [3,2-c ] quinoline-5-one derivative 南京苏亦欣医药科技有限公司 2025-01-17 CN claimed
CN-116063217-B Efficient catalyst ligand for ethylene selective trimerization, preparation method, catalyst system and application thereof 海南贝欧亿科技有限公司 2025-01-10 CN claimed
CN-119119116-A Rhein phosphoryl derivative and synthetic method and application thereof 甘肃中医药大学 2024-12-13 CN claimed
CN-119039312-A Method for preparing medical intermediate 3-benzimidazoline coumarin pyranone derivative by catalyzing acid eutectic solvent 南京欣久医药科技有限公司 2024-11-29 CN claimed
CN-119019390-A Method for preparing drug intermediate pyrimido [4,5-b ] quinoline derivative by eutectic solvent catalysis 南京苏亦欣医药科技有限公司 2024-11-26 CN claimed
CN-118955912-A Phosphazene polymer microsphere, preparation method and application 山东泰星新材料股份有限公司 2024-11-15 CN claimed
US-4369275-A PHOTOSTABILITY FOR POLYMERS CIBA-GEIGY AG (CH) 1983-01-18 US claimed
EP-0047200-A2 Method of painting a substrate, and its use in road marking COMMISSARIAT A L'ENERGIE ATOMIQUE Etablissement de Caractère Scientifique Technique et Industriel (FR) 1982-03-10 EP claimed
US-4293468-A Malonate derivatives as stabilizers for organic materials CIBA-GEIGY AG (CH) 1981-10-06 US claimed
US-4251331-A USING AN A-AMINO ALIPHATIC CARBOXYLIC ACID BRIGHTENING AGENT, AND A NONIONIC SURFACTANT; AN AQUEOUS ACID BATH COLUMBIA CHEMICAL CORPORATION (US) 1981-02-17 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US claimed
US-4010193-A (ALKYLAMINO)ALKYL SUBSTITUTED BENZOATES, LOCAL ANESTHETIC, ANTIFIBRILLATORY, ANTIARRHYTHMIAL CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) 1977-03-01 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed
US-3947450-A Benzoxanthene and benzothioxanthene dicarboxylic acid imide dyestuffs and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DT) 1976-03-30 US claimed