Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790399 | 0.84 | CYP2A6 (0.44) | CYP1A2LMNACYP2A6TSHRKDM4E | |
| SCHEMBL2012242 | 0.83 | MAPK1 (0.38) | LMNATSHRNPC1TP53RAB9A | |
| SCHEMBL5899212 | 0.83 | HPGD (0.35) | KDM4EALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL10765346 | 0.83 | NPC1 (0.44) | CYP1A2AHRCYP2A6TSHRKDM4E | |
| SCHEMBL4653269 | 0.81 | CYP1A2 (0.39) | CYP1A2AHRLMNACYP2A6ALOX5 | |
| SCHEMBL435279 | 0.79 | CYP1A2 (0.38) | CYP1A2AHRLMNACYP2A6ALOX5 | |
| SCHEMBL7733237 | 0.79 | CYP1A2 (0.38) | CYP1A2LMNACYP2A6ALOX5TSHR | |
| SCHEMBL9265689 | 0.79 | CYP1A2 (0.38) | CYP1A2AHRLMNACYP2A6ALOX5 | |
| SCHEMBL8371280 | 0.79 | CYP1A2 (0.38) | CYP1A2AHRLMNACYP2A6ALOX5 | |
| SCHEMBL16720201 | 0.79 | ALOX5 (0.45) | CYP1A2LMNACYP2A6ALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | claimed |
| EP-0414299-B1 | Biocidal azoxime compounds | SHELL INT RESEARCH (NL) | 1994-06-15 | — | — | EP | claimed |
| EP-2912178-B1 | SUPER-ENHANCERS AND METHODS OF USE THEREOF | WHITEHEAD INST BIOMEDICAL RES (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-2912178-A1 | SUPER-ENHANCERS AND METHODS OF USE THEREOF | The Whitehead Institute for Biomedical Research (US) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014066848-A9 | SUPER-ENHANCERS AND METHODS OF USE THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-08-14 | — | — | WO | disclosed |
| WO-2014066848-A1 | SUPER-ENHANCERS AND METHODS OF USE THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-05-01 | — | — | WO | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0414299-B1 | Biocidal azoxime compounds | SHELL INT RESEARCH (NL) | 1994-06-15 | — | — | EP | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0036834-B1 | PROCESS FOR THE PREPARATION OF METAL COMPLEXES OF ISOINDOLINE AZINES | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | disclosed |
| US-4405792-A | Substituted pyridines and their preparation | ETHYL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0036834-A1 | Process for the preparation of metal complexes of isoindoline azines | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036387-A2 | Process for the preparation of hydrazono-isoindolines | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |
| EP-0036388-A2 | Isoindoline derivatives, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |
| US-3992416-A | 4-Oxa-5-hydroxypolycycloalkenones-(3) | BASF AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |