Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987990 | 0.83 | ESR1 (0.42) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6607387 | 0.81 | ALDH1A1 (0.46) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9988099 | 0.80 | TRPA1 (0.37) | CYP1A2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9650164 | 0.80 | NPC1 (0.35) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16719770 | 0.79 | ESR2 (0.52) | ALOX5ARALDH1A1HSD17B10CA2 | |
| SCHEMBL16719910 | 0.79 | ALOX5 (0.55) | ALOX5NPC1RAB9AALOX15EGFR | |
| SCHEMBL435757 | 0.79 | CYP1A2 (0.41) | ALOX5CYP1A2NPC1RAB9AALDH1A1 | |
| SCHEMBL16720189 | 0.78 | ALOX5 (0.37) | ALOX5NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL4653269 | 0.78 | CYP1A2 (0.39) | ALOX5CYP1A2NPC1RAB9AALDH1A1 | |
| SCHEMBL16720369 | 0.77 | MKNK1 (0.37) | ALOX5NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |