SCHEMBL4357724

SCHEMBL4357724

C=C(C)C(=O)N(C)C.C=CC(=O)N(C)C.CC(=CC(C)C)C(N)=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1049447 0.80 ALDH1A1 (0.38) TDP1
SCHEMBL514626 0.77 TDP1 (0.55) TDP1
SCHEMBL22716232 0.73 TDP1 (0.44) TDP1
Methacrylic Acid SCHEMBL28170314 0.73 TDP1 (0.44) TDP1
Acrylamide SCHEMBL28087262 0.73 ALDH1A1 (0.50) TDP1
SCHEMBL14952 0.73
SCHEMBL14950 0.73
Ammonia Solution, Strong SCHEMBL18092981 0.71 LMNA (0.35) TDP1
SCHEMBL16159981 0.69
SCHEMBL8206258 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090011017-A1 POLYMERS BASED ON WATER-SOLUBLE MONOOLEFINIC COMPRISING COLLOIDAL SILICA AND THEIR USE AS MATRIX POLYMERS FOR SOLID DOSAGE FORMS BASF SE (DE) 2009-01-08 US disclosed