Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | FASN | P49327 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360517 | 0.91 | NAMPT (0.41) | NAMPTLMNAGPR119 | |
| SCHEMBL13586043 | 0.89 | NPY2R (0.43) | PTPN2PTPN1LMNAHTR1AHTR1B | |
| SCHEMBL4530802 | 0.88 | LMNA (0.51) | PTPN2PTPN1LMNAHTR1AHTR1B | |
| SCHEMBL13586351 | 0.87 | POLB (0.52) | NAMPTPTPN2PTPN1LMNAHTR1A | |
| SCHEMBL4541177 | 0.87 | LMNA (0.45) | NAMPTPTPN2PTPN1LMNAHTR1A | |
| SCHEMBL13586060 | 0.86 | SMN1; SMN2 (0.47) | PTPN2PTPN1LMNAALDH1A1CYP2C19 | |
| SCHEMBL13586356 | 0.86 | PTPN2 (0.41) | PTPN2PTPN1LMNAHTR1AHTR1B | |
| SCHEMBL4538611 | 0.86 | HPGD (0.42) | PTPN2PTPN1LMNAHTR1AHTR1B | |
| SCHEMBL4523985 | 0.86 | KDM4E (0.41) | NAMPTALDH1A1SMN1; SMN2GPR119 | |
| SCHEMBL13586061 | 0.85 | MEN1 (0.49) | PTPN2PTPN1LMNAALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |