Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540400 | 0.92 | GPR119 (0.35) | SMN1; SMN2HTR1AGPR119MEN1KMT2A | |
| SCHEMBL13586043 | 0.90 | NPY2R (0.43) | PTPN2PTPN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13586351 | 0.88 | POLB (0.52) | PTPN2PTPN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4530802 | 0.87 | LMNA (0.51) | PTPN2PTPN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13586060 | 0.87 | SMN1; SMN2 (0.47) | PTPN2PTPN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4352059 | 0.87 | P2RY12 (0.41) | ALDH1A1SMN1; SMN2GPR119 | |
| SCHEMBL4538611 | 0.87 | HPGD (0.42) | PTPN2PTPN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4539513 | 0.86 | POLB (0.44) | PTPN2PTPN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4358330 | 0.86 | NAMPT (0.42) | PTPN2PTPN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4541177 | 0.86 | LMNA (0.45) | PTPN2PTPN1POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |