Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541177 | 0.95 | LMNA (0.45) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL4533473 | 0.91 | LMNA (0.40) | LMNAHPGDCD274SLC6A2SLC6A4 | |
| SCHEMBL4538611 | 0.91 | HPGD (0.42) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL13586043 | 0.90 | NPY2R (0.43) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL4539513 | 0.90 | POLB (0.44) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL13586061 | 0.89 | MEN1 (0.49) | LMNAPTPN2PTPN1ALDH1A1CYP2C19 | |
| SCHEMBL4358330 | 0.88 | NAMPT (0.42) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL13586351 | 0.88 | POLB (0.52) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL4535777 | 0.88 | ALDH1A1 (0.44) | LMNAPTPN2PTPN1HTR1AHTR1B | |
| SCHEMBL13586060 | 0.88 | SMN1; SMN2 (0.47) | LMNAPTPN2PTPN1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |