Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129328 | 0.89 | CYP3A4 (0.52) | CYP3A4CYP2C9GPR119KCNH2PDE9A | |
| SCHEMBL1128224 | 0.88 | CYP3A4 (0.66) | CYP3A4CYP2C9GPR119NR3C1PIK3CD | |
| SCHEMBL1128654 | 0.88 | CYP3A4 (0.51) | CYP3A4CYP2C9GPR119KCNH2 | |
| SCHEMBL4368392 | 0.87 | CYP3A4 (0.51) | CYP3A4CYP2C9GPR119PDE9ABTK | |
| SCHEMBL4468923 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP2C9GPR119KMT2ASMN1; SMN2 | |
| SCHEMBL1129187 | 0.85 | CYP3A4 (0.61) | CYP3A4CYP2C9GPR119KCNH2 | |
| SCHEMBL4328580 | 0.85 | CYP3A4 (0.51) | CYP3A4CYP2C9GPR119KCNH2PDE9A | |
| SCHEMBL4368642 | 0.85 | GPR119 (0.49) | CYP3A4CYP2C9GPR119PDE9AFLT3 | |
| SCHEMBL1128285 | 0.85 | CYP3A4 (0.48) | CYP3A4CYP2C9GPR119KCNH2KMT2A | |
| SCHEMBL4354583 | 0.83 | CYP3A4 (0.60) | CYP3A4CYP2C9KCNH2EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | CYP3A4 1503/4885CYP2C9 917/4885GPR119 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.