Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.42 |
| ▸ | RAF1 | P04049 | 8/20 | 0.42 |
| ▸ | BRAF | P15056 | 8/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10197645 | 0.86 | FAAH (0.54) | FAAH | |
| SCHEMBL10197653 | 0.85 | ADRB3 (0.46) | FAAHRAF1BRAFACHECA1 | |
| SCHEMBL346830 | 0.84 | FAAH (0.49) | FAAHRAF1BRAF | |
| SCHEMBL461415 | 0.82 | MTNR1A (0.54) | RAF1BRAFMTNR1AMTNR1B | |
| SCHEMBL15967913 | 0.82 | RAF1 (0.45) | FAAHRAF1BRAFMTNR1AMTNR1B | |
| SCHEMBL10197685 | 0.81 | FAAH (0.60) | FAAH | |
| SCHEMBL10197649 | 0.80 | ADRB3 (0.49) | FAAH | |
| SCHEMBL10197641 | 0.80 | MTNR1A (0.60) | ACHECA1CA2MTNR1AMTNR1B | |
| SCHEMBL346899 | 0.80 | FAAH (0.54) | FAAH | |
| SCHEMBL10197716 | 0.78 | MMP8 (0.49) | RAF1BRAFMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |