(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL4359379

ClCc1ccccc1.O=S(=O)(Cl)Cl

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.46
CA1 P00915 6/20 0.46
CA9 Q16790 3/20 0.46
ELANE P08246 2/20 0.46
FAAH O00519 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRTN3 P24158 1/20 0.46
PRSS3 P35030 1/20 0.46
CA5A P35218 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA14 Q9ULX7 2/20 0.44
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL28421276 0.90 ALDH1A1 (0.44) CA2CA1CA9ELANEFAAH
(Chloromethyl)Benzene SCHEMBL29794364 0.86
(Chloromethyl)Benzene SCHEMBL29919724 0.86
(Chloromethyl)Benzene SCHEMBL4746769 0.86 CALM1 (0.53) ELANEALDH1A1HSD17B10TDP1CALM1
(Chloromethyl)Benzene SCHEMBL1616642 0.86
(Chloromethyl)Benzene SCHEMBL6422666 0.86 CALM1 (0.53) ELANEALDH1A1HSD17B10TDP1CALM1
(Chloromethyl)Benzene SCHEMBL1331085 0.86
(Chloromethyl)Benzene SCHEMBL7413 0.86
SCHEMBL21317609 0.86 CALM1 (0.53) ELANEALDH1A1HSD17B10TDP1CALM1
(Chloromethyl)Benzene SCHEMBL28213819 0.83 CALM1 (0.45) CA2CA1ELANEALDH1A1CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103305621-B Fluorescent method of 5-hydroxymethylcytosine based on FRET (Forster Resonance Energy Transfer) principle UNIV WUHAN 2015-05-13 CN disclosed
CN-103360286-A Simple preparation method for sulfonyl chloride UNIV BEIJING CHEMICAL 2013-10-23 CN disclosed
CN-103351315-A General preparation method of sulfonyl chloride UNIV BEIJING CHEMICAL 2013-10-16 CN disclosed
CN-103305621-A Fluorescent method of 5-hydroxymethylcytosine based on FRET (Forster Resonance Energy Transfer) principle UNIV WUHAN 2013-09-18 CN disclosed
CN-103193687-A Method for preparing sulfonyl chloride in environment-friendly mode UNIV BEIJING CHEMICAL 2013-07-10 CN disclosed
US-20090286837-A1 Oxadiazole compounds as urokinase inhibitors WILEX AG (DE) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286837-A1 Oxadiazole compounds as urokinase inhibitors PLAUR, PLAU, PLAT CA2 2434/4885CA1 1265/4885CA9 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.