SCHEMBL4359477

SCHEMBL4359477

[CH2]c1cccc(Oc2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.46
F10 P00742 4/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
ST14 Q9Y5Y6 1/20 0.46
HTT P42858 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LTA4H P09960 1/20 0.44
TSHR P16473 1/20 0.44
MAP4K4 O95819 1/20 0.44
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
MAPK1 P28482 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
BCAT2 O15382 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521152 0.87 LTA4H (0.58) F2F10PRSS1PRSS2PRSS3
SCHEMBL10546366 0.82 MEN1 (0.52) F2F10PRSS1PRSS2PRSS3
SCHEMBL9771220 0.82 MEN1 (0.47) F2F10PRSS1PRSS2PRSS3
SCHEMBL10546030 0.82 MEN1 (0.48) F2F10PRSS1PRSS2PRSS3
SCHEMBL10547550 0.82 F2 (0.42) F2F10PRSS1PRSS2PRSS3
SCHEMBL9771157 0.82 HTT (0.47) F2F10PRSS1PRSS2PRSS3
SCHEMBL10547271 0.80 MAP4K4 (0.52) F2F10ALDH1A1MAP4K4MAPT
SCHEMBL10548022 0.80 EGFR (0.44) F2F10HTTCYP1A2RAB9A
SCHEMBL10546772 0.80 ALDH1A1 (0.50) F2F10ALDH1A1TSHRMAPK1
SCHEMBL10544419 0.80 CYP1A2 (0.53) F2F10MAP4K4CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458060-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
EP-0458061-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
CN-1014061-B The preparation method of pyrimidine derivatives ICI PLC (GB) 1991-09-25 CN claimed
EP-0364116-A1 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-18 EP claimed
EP-0361694-A2 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-04 EP claimed
EP-0361695-A2 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-04 EP claimed
EP-0295839-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-21 EP claimed
EP-0145179-B1 HALO((PHENOXYPYRIDYL)METHYL)ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-23 EP claimed
EP-0118283-B1 PHENYL-CYCLOBUTANE CARBOXYLATES AS ARTHROPODICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1988-11-02 EP claimed
US-4762835-A INSECTICIDES, MITICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-09 US claimed
CN-86108825-A PYRIMIDINE DERIVATIVES 1987-07-22 CN claimed
EP-0227415-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-07-01 EP claimed
EP-0108679-B1 DERIVATIVES OF CYCLOPROPANE-CARBOXYLIC ACID CONTAINING AN ALKYLTHIOCARBONYL GROUP AND A HALOGEN ATOM, THEIR PREPARATION, THEIR USE AS PARASITICIDES FOR PLANTS, ANIMALS AND PREMISES, AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-02-19 EP claimed
EP-0145179-A1 Halo((phenoxypyridyl)methyl)esters, process for their preparation and their use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-06-19 EP claimed
EP-0027011-B1 INSECTICIDAL SYNERGISTIC MIXTURES OF 0,0-DIETHYL 0-(3,5,6-TRICHLORO-2-PYRIDINYL) PHOSPHOROTHIOATE AND 3-(2,2-DICHLOROETHENYL)-2,2-DIMETHYL-CYCLOPROPANE CARBOXYLIC ACID: CYANO (6-PHENOXY-2-PYRIDINYL) METHYL ESTER AND METHOD OF KILLING AND CONTROLLING INSECTS THE DOW CHEMICAL COMPANY (US) 1983-06-29 EP claimed
US-4226872-A Pyridyl esters of α-substituted amino acids ZOECON CORPORATION (US) 1980-10-07 US claimed
EP-2061312-A2 INSECTICIDAL COMPOSITION COMPRISING CYMENE Livie Biopesticides Limited (GB) 2009-05-27 EP disclosed
WO-2008015413-A2 INSECTICIDAL COMPOSITION COMPRISING CYMENE LIVIE BIOPESTICIDES LIMITED (GB) 2008-02-07 WO disclosed
US-4224330-A Esters and thiolesters of benzothienyl acids ZOECON CORPORATION (US) 1980-09-23 US disclosed
US-4223033-A Substituted pyridine methyl esters of naphthyl acids ZOECON CORPORATION (US) 1980-09-16 US disclosed