Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546030 | 0.85 | MEN1 (0.48) | MEN1KMT2AALDH1A1NPC1HTT | |
| SCHEMBL4359477 | 0.82 | F2 (0.46) | MEN1KMT2AALDH1A1NPC1HTT | |
| SCHEMBL9771157 | 0.81 | HTT (0.47) | MEN1KMT2AHTTF2F10 | |
| SCHEMBL10547550 | 0.81 | F2 (0.42) | ALDH1A1HPGDMAP4K4F2F10 | |
| SCHEMBL9771220 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1HTTATM | |
| SCHEMBL10546373 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1NPC1HTT | |
| SCHEMBL10544866 | 0.81 | LTA4H (0.50) | ALDH1A1NPC1RAB9AHPGDF2 | |
| SCHEMBL21330627 | 0.78 | MEN1 (0.52) | MEN1KMT2AALDH1A1NPC1HTT | |
| SCHEMBL4371488 | 0.78 | MAP4K4 (0.53) | MEN1KMT2AALDH1A1NPC1HTT | |
| SCHEMBL10546772 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |