Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | CBFB | Q13951 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27899516 | 0.83 | NOS3 (0.35) | STAT3STAT1NOS3NOS1NOS2 | |
| Iodide SCHEMBL11338884 | 0.81 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM | |
| SCHEMBL460723 | 0.81 | NPC1 (0.41) | METAP2METAP1CBFBNPC1PKM | |
| SCHEMBL4359475 | 0.81 | STAT3 (0.49) | CCR1CCR5CCR8METAP2METAP1 | |
| SCHEMBL28446738 | 0.80 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM | |
| SCHEMBL31229487 | 0.80 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM | |
| SCHEMBL31678981 | 0.80 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM | |
| SCHEMBL28757530 | 0.80 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM | |
| Iodide SCHEMBL11325081 | 0.80 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM | |
| SCHEMBL6071532 | 0.80 | NPC1 (0.40) | METAP2METAP1CBFBNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101601635-A | The prescription of little RNA/DNA whitening product and manufacture method | QINWEI YIN (CN) | 2009-12-16 | — | — | CN | disclosed |
| WO-2009011697-A1 | RNA OLIGONUCLEOTIDES TARGETING EBV AND HOST GENES AND THEIR USE FOR TREATMENT OF NASOPHARYNGEAL CARCINOMAS | OLIGOS ETC. INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| EP-1093373-A4 | OLIGONUCLEOTIDE INHIBITORS OF bcl-xL | UNIV COLUMBIA (US) | 2005-04-13 | — | — | EP | disclosed |
| CN-1506041-A | Formulation and making process of genetic skin beautifying and whitening cosmetics | 殷冬生 | 2004-06-23 | — | — | CN | disclosed |
| CN-1427008-A | Method of designing and selecting natural siRNA as gene medicine and medicine formulation | YIN DONGSHENG (CN) | 2003-07-02 | — | — | CN | disclosed |
| EP-1093373-A1 | OLIGONUCLEOTIDE INHIBITORS OF bcl-xL | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000001393-A2 | OLIGONUCLEOTIDE INHIBITORS OF bcl-xL | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2000-01-13 | — | — | WO | disclosed |