Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL396674 | 0.75 | CTSD (0.32) | — | |
| Hydrochloric Acid SCHEMBL7924783 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5888444 | 0.73 | CTSD (0.31) | — | |
| Hydrochloric Acid SCHEMBL4461086 | 0.71 | CA4 (0.30) | — | |
| Iodide SCHEMBL863900 | 0.70 | CTSD (0.32) | — | |
| Fluoride Ion SCHEMBL864717 | 0.70 | CTSD (0.32) | — | |
| SCHEMBL4577187 | 0.70 | CTSD (0.32) | — | |
| Bromide SCHEMBL863746 | 0.70 | CTSD (0.32) | — | |
| Hydrochloric Acid SCHEMBL7919502 | 0.70 | L3MBTL1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL392238 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277934-B1 | A SYNDIOTACTIC HOMO- OR COPOLYMER FROM A STYRENIC COMPOUND IN THE PRESENCE OF A METALLOCENE OF HIGH, STABLE ACTIVITY COMPRISING A TITANIUM COMPOUND AND AN ORGANIC ALUMINOXY COMPOUND OF SPECIFIC NUCLEAR MAGNETIC RESONANCE SPECTRUM | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | claimed |
| US-5023304-A | Using coordination catalyst; highly syndiotactic | IDEMITSU KOSAN CO., LTD. (JP) | 1991-06-11 | — | — | US | claimed |
| EP-1777239-B1 | Half-metallocene catalyst and process for preparing syndiotactic styrene polymer using the same | LG CHEMICAL LTD (KR) | 2014-09-10 | — | — | EP | disclosed |
| US-7592401-B2 | Multinuclear half metallocene catalyst and method for preparing syndiotatic polystyrene using the same | LG CHEM, LTD. (KR) | 2009-09-22 | — | — | US | disclosed |
| US-7592404-B2 | Half metallocene catalyst and process for preparing syndiotactic styren polymer using the same | LG CHEM, LTD. (KR) | 2009-09-22 | — | — | US | disclosed |
| US-20070105710-A1 | Half metallocene catalyst and process for preparing syndiotactic styren polymer using the same | LG CHEM, LTD. (KR) | 2007-05-10 | — | — | US | disclosed |
| US-20070100095-A1 | Multinuclear half metallocene catalyst and method for preparing syndiotatic polystyren using the same | LG CHEM, LTD. (KR) | 2007-05-03 | — | — | US | disclosed |
| EP-1777230-A1 | Multinuclear half metallocene catalyst and method for preparing syndiotactic polystyrene using the same | LG Chem Ltd. (KR) | 2007-04-25 | — | — | EP | disclosed |
| EP-1777239-A1 | Half-metallocene catalyst and process for preparing syndiotactic styrene polymer using the same | LG Chem Ltd. (KR) | 2007-04-25 | — | — | EP | disclosed |
| US-7026406-B1 | Syndiotactic styrene polymers and process for the production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2006-04-11 | — | — | US | disclosed |
| US-6995218-B2 | Metallocene catalysts for olefin or styrene polymerization and polymerization method using the metallocene catalysts | SAMSUNG GENERAL CHEMICALS CO. LTD. (KR) | 2006-02-07 | — | — | US | disclosed |
| EP-0493678-A2 | Process for producing a styrene polymer and a catalyst for use therein | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0490269-A1 | Graft copolymer and process for producing the same | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-06-17 | — | — | EP | disclosed |
| EP-0444206-A1 | SLIPPERY FILM AND PRODUCTION THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-09-04 | — | — | EP | disclosed |
| EP-0440014-A2 | Process for producing a styrene polymer composition | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-5023304-A | Using coordination catalyst; highly syndiotactic | IDEMITSU KOSAN CO., LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0422239-A1 | STYRENIC COPOLYMER AND PRODUCTION THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0420134-A2 | Process for producing styrene polymers | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0410361-A2 | Process for producing styrene polymers | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-01-30 | — | — | EP | disclosed |
| EP-0389981-A2 | Process for producing styrene-based polymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-03 | — | — | EP | disclosed |