Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GNG2 | P59768 | 2/20 | 0.36 |
| ▸ | GNB1 | P62873 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437497 | 0.85 | NR4A2 (0.62) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL436731 | 0.81 | KDM4E (0.56) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL439805 | 0.80 | NR4A2 (0.47) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL442077 | 0.78 | NR4A2 (0.45) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL438887 | 0.77 | MCHR1 (0.44) | KDM4EMAPTALDH1A1 | |
| SCHEMBL440270 | 0.74 | NR4A2 (0.62) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL6588144 | 0.73 | NR4A2 (0.60) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL438224 | 0.72 | NR4A2 (0.69) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL17506375 | 0.70 | MAPT (0.45) | NR4A2KDM4ETDP1MAPTPOLB | |
| SCHEMBL440491 | 0.70 | NR4A2 (0.74) | NR4A2NCF1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |