Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440270 | 0.85 | NR4A2 (0.62) | NR4A2NCF1ALDH1A1HTTCRHR1 | |
| SCHEMBL436019 | 0.85 | NR4A2 (0.53) | NR4A2BCHEACHEGRIN1GRIN2A | |
| SCHEMBL4744678 | 0.82 | CRHR1 (0.50) | NR4A2BCHEACHEGRIN1GRIN2A | |
| SCHEMBL439805 | 0.80 | NR4A2 (0.47) | NR4A2NCF1CRHR1KDM4ETDP1 | |
| SCHEMBL4745138 | 0.78 | KMT2A (0.42) | NR4A2BCHEACHEGRIN1GRIN2A | |
| SCHEMBL438980 | 0.76 | NR4A2 (1.00) | NR4A2ACHENCF1ALDH1A1CRHR1 | |
| SCHEMBL439708 | 0.75 | MCHR1 (0.43) | NR4A2BCHEACHEGRIN1GRIN2A | |
| SCHEMBL439768 | 0.73 | NR4A2 (0.65) | NR4A2NCF1ALDH1A1CRHR1KDM4E | |
| SCHEMBL439579 | 0.73 | NR4A2 (0.65) | NR4A2NCF1ALDH1A1CRHR1KDM4E | |
| SCHEMBL439576 | 0.70 | NR4A2 (0.54) | NR4A2BCHEACHENCF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |