Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437497 | 0.80 | NR4A2 (0.62) | NR4A2HSP90AA1HSP90AB1MAPTCRHR1 | |
| SCHEMBL436019 | 0.80 | NR4A2 (0.53) | NR4A2MAPTCRHR1NCF1KDM4E | |
| SCHEMBL441787 | 0.78 | MCHR1 (0.37) | HSP90AA1HSP90AB1MAPTCRHR1 | |
| SCHEMBL437287 | 0.75 | NR4A2 (0.61) | NR4A2HSP90AA1MAPTCRHR1NCF1 | |
| SCHEMBL10099094 | 0.75 | CXCL12 (0.40) | HSP90AA1HSP90AB1MAPTCRHR1GAA | |
| SCHEMBL9860481 | 0.73 | G6PD (0.49) | NR4A2HSP90AA1HSP90AB1MAPTCRHR1 | |
| SCHEMBL438207 | 0.73 | MAPT (0.53) | NR4A2HSP90AA1HSP90AB1MAPTCRHR1 | |
| SCHEMBL27296032 | 0.71 | SMN1; SMN2 (0.35) | MAPTCRHR1GAAKDM4E | |
| SCHEMBL441437 | 0.70 | MAPT (0.57) | NR4A2HSP90AA1HSP90AB1MAPTCRHR1 | |
| SCHEMBL14498166 | 0.69 | SLC2A1 (0.55) | NR4A2NCF1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |