Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128169 | 0.94 | — | — | |
| SCHEMBL246838 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL8596055 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL105 | 0.94 | — | — | |
| SCHEMBL15109974 | 0.94 | — | — | |
| SCHEMBL25599 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL579101 | 0.89 | — | — | |
| SCHEMBL22749161 | 0.89 | — | — | |
| SCHEMBL429367 | 0.89 | — | — | |
| SCHEMBL20570964 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768962-B | Leaving group is the platinum-like compounds of the malonate derivative containing amino or alkylamino | 北京市丰硕维康技术开发有限责任公司 | 2017-04-05 | — | — | CN | claimed |
| CN-103703011-B | Platinum compounds with leaving group of hydroxy acid derivative containing amino or alkylamino, and preparation method and application thereof | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | claimed |
| US-11013730-B1 | Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith | THIOREDOXIN SYSTEMS AB (SE) | 2021-05-25 | — | — | US | disclosed |
| US-10058542-B1 | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith | THIOREDOXIN SYSTEMS AB (SE) | 2018-08-28 | — | — | US | disclosed |
| EP-2740738-B1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) | 2018-03-28 | — | — | EP | disclosed |
| CN-104995201-B | Platinum (II) compound for treating tumor cell proliferative diseases | 北京市丰硕维康技术开发有限责任公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-104768962-B | Leaving group is the platinum-like compounds of the malonate derivative containing amino or alkylamino | 北京市丰硕维康技术开发有限责任公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-2759547-B1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | BEIJING FSWELCOME TECH DEV CO LTD (CN) | 2017-01-18 | — | — | EP | disclosed |
| CN-103649100-B | Platinum compound with leaving group of succinic acid derivative containing amino or alkylamino, preparation method and application thereof | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103732601-B | The one class treatment platinum compounds of cell proliferation disorders, its preparation method and application | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103703011-B | Platinum compounds with leaving group of hydroxy acid derivative containing amino or alkylamino, and preparation method and application thereof | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-102993239-A | Platinum compound of succinic acid derivative with leaving group containing amino or alkylamino | CHEN XIAOPING | 2013-03-27 | — | — | CN | disclosed |
| CN-102863474-A | Platinum compounds for treating cell proliferative diseases and preparation method and application thereof | CHEN XIAOPING | 2013-01-09 | — | — | CN | disclosed |
| EP-2043611-A2 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | Nucryst Pharmaceuticals Corp. (CA) | 2009-04-08 | — | — | EP | disclosed |
| WO-2009014781-A2 | METAL-CONTAINING MATERIALS FOR TREATMENT OF BACTERIAL CONDITIONS | NUCRYST PHARMACEUTICALS CORP. (CA) | 2009-01-29 | — | — | WO | disclosed |
| US-20080050452-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-02-28 | — | — | US | disclosed |
| US-20080044491-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-02-21 | — | — | US | disclosed |
| US-20080014247-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-01-17 | — | — | US | disclosed |
| US-20080014278-A1 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS | 2008-01-17 | — | — | US | disclosed |
| WO-2008005705-A2 | METAL-CONTAINING FORMULATIONS AND METHODS OF USE | NUCRYST PHARMACEUTICALS CORP. (CA) | 2008-01-10 | — | — | WO | disclosed |