Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369016 | 0.97 | PLA2G4A (0.67) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1144832 | 0.92 | KDM4E (0.65) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6469163 | 0.92 | KDM4E (0.60) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13174431 | 0.86 | KDM4E (0.62) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2767179 | 0.86 | KDM4E (0.65) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24076666 | 0.86 | PLA2G4A (0.55) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| Anthranilamide SCHEMBL6469157 | 0.86 | PLA2G4A (0.54) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4371734 | 0.86 | PDGFRB (0.71) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4816031 | 0.85 | KDM4E (0.64) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3033147 | 0.85 | KDM4E (0.67) | PLA2G4AKDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |