Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469163 | 0.92 | KDM4E (0.60) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL4360657 | 0.86 | PLA2G4A (0.68) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL4369016 | 0.84 | PLA2G4A (0.67) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| Anthranilamide SCHEMBL6335928 | 0.83 | HSD17B10 (0.55) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL1144832 | 0.79 | KDM4E (0.65) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL6469159 | 0.79 | HDAC1 (0.63) | ALDH1A1KDM4EPDGFRBPDGFRAMAPT | |
| SCHEMBL9816433 | 0.77 | KDM4E (0.73) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL13174431 | 0.74 | KDM4E (0.62) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL24076666 | 0.74 | PLA2G4A (0.55) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL2767179 | 0.74 | KDM4E (0.65) | PLA2G4AALDH1A1KDM4EHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005508311-A | — | — | 2005-03-31 | — | — | JP | claimed |
| EP-1416928-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | claimed |
| WO-2003013484-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-02-20 | — | — | WO | claimed |