Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359243 | 0.93 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4345582 | 0.90 | HTR4 (0.45) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3943428 | 0.88 | MET (0.44) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3950110 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4362231 | 0.85 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3950664 | 0.85 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4353016 | 0.83 | HTR4 (0.45) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4347559 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3951180 | 0.82 | MAPT (0.48) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3941326 | 0.82 | MAPT (0.48) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |