SCHEMBL4361332

SCHEMBL4361332

COc1ccc(C(C#N)=NOS(=O)(=O)c2ccc(C)cc2)cc1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
PKM P14618 2/20 0.48
HPGD P15428 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PAX8 Q06710 1/20 0.48
GFER P55789 1/20 0.45
CTNNB1 P35222 1/20 0.44
WNT3A P56704 1/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 4/20 0.42
LMNA P02545 3/20 0.42
HTT P42858 3/20 0.41
ATM Q13315 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
PDE4B Q07343 2/20 0.40
PDE4A P27815 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40
KDM4E B2RXH2 1/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4361330 1.00 ALDH1A1 (0.48) ALDH1A1PKMHPGDSMN1; SMN2PAX8
SCHEMBL7781706 0.91 PDE4A (0.47) ALDH1A1GAAMAPTLMNAPDE4B
SCHEMBL7781708 0.91 PDE4A (0.47) ALDH1A1GAAMAPTLMNAPDE4B
SCHEMBL1331529 0.90 ALDH1A1 (0.41) ALDH1A1PKMHPGDSMN1; SMN2PAX8
SCHEMBL1331531 0.90 ALDH1A1 (0.41) ALDH1A1PKMHPGDSMN1; SMN2PAX8
SCHEMBL7786880 0.89 MAPT (0.47) ALDH1A1PKMGAAMAPTLMNA
SCHEMBL7786882 0.89 MAPT (0.47) ALDH1A1PKMGAAMAPTLMNA
SCHEMBL7786962 0.89 NPC1 (0.47) ALDH1A1PKMHPGDSMN1; SMN2GAA
SCHEMBL7786960 0.89 NPC1 (0.47) ALDH1A1PKMHPGDSMN1; SMN2GAA
SCHEMBL7790744 0.88 ALDH1A1 (0.38) ALDH1A1PKMHPGDSMN1; SMN2PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090207286-A1 Colored photosensitive composition, and color filter array and solid image pickup device using the same SONY CORPORATION (JP) 2009-08-20 US disclosed
US-20090207287-A1 Colored photosensitive composition, and color filter array and solid image pickup device using the same SONY CORPORATION (JP) 2009-08-20 US disclosed
US-20080237553-A1 Colored photosensitive resin composition, and color filter array and solid-state image pickup device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2008-10-02 US disclosed
US-20080237554-A1 Colored photosensitive resin composition, and color filter array and solid-state image pickup device using the same SUMITOMO CHEMICAL COMPANY LIMITED 2008-10-02 US disclosed
US-20070287087-A1 Colored photosensitive resin composition, color filter, image sensor, and camera system SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-12-13 US disclosed
EP-1860502-A1 Colored photosensitive resin composition, color filter, image sensor, and camera system Sumitomo Chemical Company, Limited (JP) 2007-11-28 EP disclosed
EP-1860503-A2 Colored photosensitive resin composition, color filter, image sensor, and camera system Sumitomo Chemical Company, Limited (JP) 2007-11-28 EP disclosed
US-6569596-B1 Photoresists comprising N-(ethylsulfonyloxy)succinimide, novolaks, curing agents and an acid generators such as alpha -(hexylsulfonyloxyimino)-4-methoxybenzyl cyanide; integrated circuits; semiconductors SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-05-27 US disclosed
US-20010037037-A1 Oximesulfonic acid esters and the use thereof as latent sulfonic acids CIBA SPEICIALTY CHEMICALS CORP. 2001-11-01 US disclosed
US-6017675-A POLYMERIZATION CATALYST CIBA SPECIALTY CHEMIALS CORPORATION (US) 2000-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037037-A1 Oximesulfonic acid esters and the use thereof as latent sulfonic acids QSOX1, HAO2, PAH ALDH1A1 160/4885PKM 1733/4885HPGD 779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.