Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235182 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL188276 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL229592 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11765795 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL11763847 | 0.83 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL229764 | 0.80 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL5598313 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL187847 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL188423 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL188030 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281200-A1 | ORGANOSOL OF FLUORIDE COLLOID PARTICLE AND METHOD FOR PRODUCTION THEREOF | NISSAN CHEMICAL INDUSTRIAL, LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-4026826-A | ALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-05-31 | — | — | US | disclosed |