Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435693 | 0.86 | SSTR4 (0.33) | GHSR | |
| SCHEMBL434259 | 0.85 | F10 (0.39) | FAAHGHSRHDAC1 | |
| SCHEMBL435890 | 0.85 | FAAH (0.37) | FAAH | |
| SCHEMBL345716 | 0.77 | KHK (0.40) | GHSRHDAC1 | |
| SCHEMBL346196 | 0.77 | GSK3B (0.46) | FAAH | |
| SCHEMBL436179 | 0.77 | GRIA2 (0.35) | FAAHOPRM1OPRD1OPRK1GHSR | |
| SCHEMBL460073 | 0.75 | HDAC1 (0.41) | FAAHGHSRHDAC1 | |
| SCHEMBL346598 | 0.74 | KHK (0.40) | GHSRHDAC1HDAC8 | |
| SCHEMBL346787 | 0.71 | GRIA2 (0.40) | FAAHOPRM1OPRD1OPRK1GHSR | |
| SCHEMBL436428 | 0.71 | RAF1 (0.32) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |