Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435693 | 0.83 | SSTR4 (0.33) | RAF1BRAFPOLBAPEX1KARS1 | |
| SCHEMBL435694 | 0.79 | GHSR (0.35) | GHSRCA1CA2ACHE | |
| SCHEMBL346598 | 0.78 | KHK (0.40) | RAF1BRAFGHSR | |
| SCHEMBL10265063 | 0.74 | RAF1 (0.41) | RAF1BRAFGHSRCA1CA2 | |
| SCHEMBL436766 | 0.74 | NR1H2 (0.39) | — | |
| SCHEMBL436765 | 0.74 | ALDH1A1 (0.39) | POLB | |
| SCHEMBL345716 | 0.74 | KHK (0.40) | GHSR | |
| SCHEMBL436178 | 0.71 | FAAH (0.35) | GHSR | |
| SCHEMBL346082 | 0.70 | MMP3 (0.40) | RAF1BRAF | |
| SCHEMBL436179 | 0.70 | GRIA2 (0.35) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |