Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 11/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435694 | 0.87 | GHSR (0.35) | GHSROPRM1OPRD1OPRK1 | |
| SCHEMBL435891 | 0.85 | FAAH (0.36) | FAAHOPRM1OPRD1OPRK1 | |
| SCHEMBL434259 | 0.81 | F10 (0.39) | GRIA2FAAHGHSRAAK1HDAC1 | |
| SCHEMBL436178 | 0.77 | FAAH (0.35) | FAAHGHSROPRM1OPRD1OPRK1 | |
| SCHEMBL12505567 | 0.77 | FAAH (0.36) | FAAHGHSR | |
| SCHEMBL436726 | 0.74 | GHSR (0.42) | GHSRHDAC1HDAC2HDAC8 | |
| SCHEMBL346196 | 0.73 | GSK3B (0.46) | FAAH | |
| SCHEMBL345716 | 0.73 | KHK (0.40) | GHSRHDAC1MCHR1 | |
| SCHEMBL460073 | 0.71 | HDAC1 (0.41) | GRIA2FAAHGHSRHDAC1MCHR1 | |
| SCHEMBL346787 | 0.71 | GRIA2 (0.40) | GRIA2FAAHGHSROPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |