SCHEMBL436220

SCHEMBL436220

CCC=COCCCc1ccc(N(CCC)CCC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 2/20 0.38
GMNN O75496 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
GABRA1 P14867 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
THPO P40225 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
SLCO1B3 Q9NPD5 1/20 0.35
BCHE P06276 2/20 0.33
HDAC6 Q9UBN7 1/20 0.33
RORC P51449 1/20 0.32
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436343 0.91 ESRRG (0.39) ESRRGMAPTRORCSIGMAR1
SCHEMBL435789 0.88 ALDH1A1 (0.39) ESRRGALDH1A1LMNAMAPTTSHR
SCHEMBL438128 0.84 CHKA (0.41) ALDH1A1MAPTTSHRNFKB1SMN1; SMN2
SCHEMBL434187 0.82 ESRRG (0.38) ESRRGALDH1A1MAPTSMN1; SMN2BCHE
SCHEMBL434880 0.79 ALDH1A1 (0.41) ESRRGALDH1A1LMNAMAPTTSHR
SCHEMBL436833 0.74 CALM1 (0.42) ALDH1A1TSHR
SCHEMBL19392314 0.73 ESR1 (0.55) ALDH1A1LMNAHIF1AEGFRSIGMAR1
SCHEMBL15127586 0.73 ESRRG (0.49) ESRRGGMNNALDH1A1LMNACYP2D6
SCHEMBL15127587 0.72 ESRRG (0.44) ESRRGGMNNALDH1A1LMNACYP2D6
SCHEMBL438068 0.69 ALDH1A1 (0.43) ESRRGALDH1A1LMNAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US disclosed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US disclosed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed