SCHEMBL436833

SCHEMBL436833

CCC=COCCc1ccc(N(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 2/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CHKA P35790 3/20 0.37
APP P05067 3/20 0.36
HRH3 Q9Y5N1 2/20 0.34
CNR2 P34972 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438128 0.90 CHKA (0.41) CALM1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL434880 0.85 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL435294 0.83 ALDH1A1 (0.45) CALM1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL436343 0.83 ESRRG (0.39) MAPK1CNR2
SCHEMBL9536656 0.77 ALDH1A1 (0.47) CALM1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL435789 0.76 ALDH1A1 (0.39) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL436220 0.74 ESRRG (0.38) ALDH1A1TSHR
SCHEMBL14524153 0.73 TSHR (0.50) CALM1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL4068305 0.72 CALM1 (0.56) CALM1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL4405018 0.71 ALDH1A1 (0.70) CALM1ALDH1A1TSHRCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US disclosed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US disclosed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed