Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27526716 | 0.97 | HSD17B10 (0.60) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL4363737 | 0.94 | HSD17B10 (0.57) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL9198996 | 0.90 | ALDH1A1 (0.60) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL9019642 | 0.88 | HSD17B10 (0.57) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL28417890 | 0.88 | HSD17B10 (0.57) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL7923883 | 0.83 | HSD17B10 (0.67) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL83488 | 0.83 | HSD17B10 (0.67) | HSD17B10ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL9350715 | 0.80 | — | — | |
| SCHEMBL1290362 | 0.80 | — | — | |
| SCHEMBL9131234 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930318-B1 | Process for producing diphenyl sulfone compound | NIPPON SODA CO (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-1273570-B1 | PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND | NIPPON SODA CO (JP) | 2013-07-17 | — | — | EP | disclosed |
| US-7619120-B2 | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO., LTD. (JP) | 2009-11-17 | — | — | US | disclosed |
| EP-1930318-A2 | Process for producing diphenyl sulfone compound | Nippon Soda Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-20050065377-A1 | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO., LTD | 2005-03-24 | — | — | US | disclosed |
| US-6831201-B2 | Aqueous solution containing dihydroxydiphenyl sulfone monoether compound is adjusted pH to a preset value, extracted with an organic solvent and separated to an organic and an aqueous layers, and that water or water adjusted to a fixed pH | NIPPON SODA CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| US-20030092941-A1 | Process for producing diphenyl sulfone compound | NIPPON SODA CO., LTD. (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1273570-A1 | PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND | NIPPON SODA CO., LTD. (JP) | 2003-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092941-A1 | Process for producing diphenyl sulfone compound | ASH2L, AP2S1, HACL2 | HSD17B10 2476/4885ALDH1A1 943/4885CYP2C9 1951/4885 |
| US-20050065377-A1 | Processes for the preparation of diphenylsulfone compounds | AP2S1, ASH2L, SRMS | HSD17B10 1832/4885ALDH1A1 1118/4885CYP2C9 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.