SCHEMBL31025927

SCHEMBL31025927

Cc1c(C(=O)O)[nH]c2cc(Cl)c(Cl)cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
NPY1R P25929 1/20 0.50
NPY2R P49146 1/20 0.50
KMT2A Q03164 1/20 0.50
GPR35 Q9HC97 3/20 0.44
GRIN1 Q05586 2/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
GRIA4 P48058 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025901 0.89 MEN1 (0.48) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025891 0.88 GPR35 (0.51) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025896 0.86 GPR35 (0.46) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025917 0.86 PTGS1 (0.48) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025898 0.84 MTNR1A (0.50) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025894 0.82 FASN (0.48) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025930 0.81 ALDH1A1 (0.58) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL8752566 0.80 GPR35 (0.43) GPR35GRIN1GRIN2DGRIN3BGRIA1
SCHEMBL11784003 0.79 GPR35 (0.66) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL1144990 0.79 GPR17 (0.60) MEN1KMT2AGRIN1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed