Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C | P53041 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TKT | P29401 | 7/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364375 | 0.84 | PPP5C (0.82) | PPP5CTDP1LMNATKTHSP90AA1 | |
| SCHEMBL31477791 | 0.74 | PPP5C (0.70) | PPP5CTDP1LMNATKTHSP90AA1 | |
| SCHEMBL2512165 | 0.72 | PPP5C (0.68) | PPP5CTDP1LMNATKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL1533810 | 0.71 | PPP5C (0.67) | PPP5CTDP1LMNATKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL3908684 | 0.69 | PPP5C (0.64) | PPP5CTDP1LMNATKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL5709836 | 0.69 | TDP1 (0.60) | PPP5CTDP1LMNATKTHSP90AA1 | |
| SCHEMBL13741845 | 0.68 | TKT (0.71) | PPP5CTDP1TKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL4355811 | 0.67 | TKT (0.70) | PPP5CTDP1TKTHSP90AA1 | |
| SCHEMBL30249786 | 0.66 | LMNA (0.66) | PPP5CTDP1LMNATKTHSP90AA1 | |
| Pyrophosphoric Acid SCHEMBL2464363 | 0.66 | TKT (0.54) | PPP5CTDP1LMNATKTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |