Sugi Predict

Sugi Predict / Compounds / SCHEMBL4364384

SCHEMBL4364384

SCHEMBL4364384

O=C(Nc1ccccc1)Nc1cccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CXCR2 P25025 4/20 0.74
▸ CXCR1 P25024 3/20 0.74
▸ LMNA P02545 6/20 0.72
▸ MAPT P10636 8/20 0.63
▸ GAA P10253 4/20 0.63
▸ ALDH1A1 P00352 3/20 0.63
▸ POLB P06746 2/20 0.63
▸ APP P05067 1/20 0.59
▸ MEN1 O00255 6/20 0.55
▸ KMT2A Q03164 6/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.55
▸ HTT P42858 2/20 0.55
▸ MAPK1 P28482 2/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ RAB9A P51151 1/20 0.55
▸ CA12 O43570 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ CASP7 P55210 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4388940 0.88 CXCR2 (0.78) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL7491596 0.85 CXCR2 (1.00) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL31061375 0.85 CXCR2 (1.00) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL169338 0.83 POLB (0.54) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL169339 0.83 POLB (0.54) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL6205171 0.81 KMT2A (0.54) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL3205552 0.80 TDP1 (0.74) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL11332310 0.79 KMT2A (0.73) CXCR2CXCR1LMNAMAPTGAA
SCHEMBL1247252 0.78 PKM (0.56) CXCR2CXCR1LMNAMAPTALDH1A1
SCHEMBL7488459 0.78 CXCR2 (0.85) CXCR2CXCR1LMNAMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250172532-A1 METHOD FOR DETECTING FOOD CONTAMINATION USING STABLE ISOTOPE-LABELED STANDARDS NASIRI, Azadeh (IR) 2025-05-29 — — US claimed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 — — WO claimed
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2017-10-12 — — US claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 — — US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 — — US claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 — — US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 — — EP claimed
US-20250312349-A1 COMPOSITION AND METHODS OF TREATING INTRACELLULAR PATHOGEN INFECTION UNIV HOSPITALS CLEVELAND MEDICAL CENTER (US) 2025-10-09 — — US disclosed
US-20250172532-A1 METHOD FOR DETECTING FOOD CONTAMINATION USING STABLE ISOTOPE-LABELED STANDARDS NASIRI, Azadeh (IR) 2025-05-29 — — US disclosed
WO-2024033723-A1 METHOD FOR DETECTING FOOD CONTAMINATION USING STABLE ISOTOPE-LABELED STANDARDS NASIRI AZADEH (IR) 2024-02-15 — — WO disclosed
US-11566012-B2 Methods for treating protozoan infections NEOCULI PTY LTD (AU) 2023-01-31 — — US disclosed
EP-3188722-B1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2021-08-04 — — EP disclosed
US-20210009552-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2021-01-14 — — US disclosed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 — — EP disclosed
WO-2002032426-A1 FURTHER IMPROVEMENTS IN AND RELATING TO THE CONTROL OF COCCIDIA BOMAC RESEARCH LIMITED (NZ) 2002-04-25 — — WO disclosed
US-5494931-A ANTICOCCIDIAL IN POULTRY, PREVENTING AND TREATING SWINE DYSENTERY, GROWTH PROMOTER IN CATTLE AND SWINE PFIZER INC. (US) 1996-02-27 — — US disclosed
EP-0553106-A1 ANTICOCCIDIAL AND GROWTH PROMOTING POLYCYCLIC ETHER ANTIBIOTIC. PFIZER (US) 1993-08-04 — — EP disclosed
WO-1992006091-A1 ANTICOCCIDIAL AND GROWTH PROMOTING POLYCYCLIC ETHER ANTIBIOTIC PFIZER INC. (US) 1992-04-16 — — WO disclosed
CN-1038838-A POLYETHER ANTIBIOTIC LILLY CO ELI (US) 1990-01-17 — — CN disclosed
WO-1989006963-A1 ACIDIC POLYCYCLIC ETHER ANTIBIOTIC HAVING ANTICOCCIDIAL AND GROWTH PROMOTANT ACTIVITY PFIZER INC. (US) 1989-08-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11566012-B2 Methods for treating protozoan infections DPM1, ABCB11, PIGS CXCR2 2175/4885CXCR1 479/4885LMNA 2337/4885
US-20210009552-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS CXCR2 2175/4885CXCR1 479/4885LMNA 2337/4885
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS CXCR2 2175/4885CXCR1 479/4885LMNA 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.