Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229716 | 0.85 | EZH2 (0.59) | EZH2KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL7581044 | 0.79 | CDK2 (0.42) | KDM4ERAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL4364499 | 0.77 | PDGFRB (0.44) | KDM4EMAPTKMT2AMEN1CYP2A6 | |
| SCHEMBL7581053 | 0.76 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL10799120 | 0.73 | RAB9A (0.54) | KDM4ERAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL27996514 | 0.72 | KDM4E (0.56) | KDM4ERAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL11654524 | 0.71 | MAPT (0.51) | KDM4ERAB9AMAPTALDH1A1KMT2A | |
| Acetone SCHEMBL11664776 | 0.71 | MAPT (0.48) | KDM4ERAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL11654006 | 0.70 | MAPT (0.57) | EZH2KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL7916199 | 0.70 | ALDH1A1 (0.47) | KDM4ERAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853255-A4 | METHODS FOR TREATING ARTHRITIS USING TRIHETEROCYCLIC COMPOUNDS | GEMIN X PHARMACEUTICALS CANADA (CA) | 2009-07-08 | — | — | EP | disclosed |
| EP-1853255-A1 | METHODS FOR TREATING ARTHRITIS USING TRIHETEROCYCLIC COMPOUNDS | Gemin X Biotechnologies Inc. (CA) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006089397-A1 | METHODS FOR TREATING ARTHRITIS USING TRIHETEROCYCLIC COMPOUNDS | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2006-08-31 | — | — | WO | disclosed |