Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679115 | 1.00 | CA2 (0.65) | CA2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL27659000 | 0.93 | CA2 (0.67) | CA2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL4366751 | 0.93 | CA2 (0.67) | CA2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7442014 | 0.90 | CA2 (0.74) | CA2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7442005 | 0.90 | CA2 (0.74) | CA2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL4356215 | 0.90 | RAB9A (0.58) | CA2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL4369236 | 0.87 | CTSL (0.67) | CA2CA1PTPN1MMECTSL | |
| SCHEMBL11582248 | 0.87 | CTSL (0.67) | CA2CA1PTPN1MMECTSL | |
| SCHEMBL13669589 | 0.87 | CTSL (0.67) | CA2CA1PTPN1MMECTSL | |
| SCHEMBL28760302 | 0.87 | CTSL (0.67) | CA2CA1PTPN1MMECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | claimed |
| US-9023809-B2 | Phenylalanine dipeptide derivatives, compositions and use thereof | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY OF SCIENCES (CN) | 2015-05-05 | — | — | US | disclosed |
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | disclosed |
| CN-100480234-C | N-(N-benzoyl-phenylalanyl)-phenylalanine dipeptide derivative, and preparing method and use thereof | KEY LAB OF CHEMISTRY FOR NATUR (CN) | 2009-04-22 | — | — | CN | disclosed |
| CN-1935779-A | N-(N-benzoyl-phenylalanyl)-phenylalanine dipeptide derivative, and its preparing method and use | NATURAL PRODUCT CHEMISTRY KEY (CN) | 2007-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | DNPEP, PEPD, VIP | CA2 4136/4885NPC1 1535/4885RAB9A 2865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.