SCHEMBL4364577

SCHEMBL4364577

CCCCCCCCCCCCCCCCCCNC(=O)CC(C(=O)O)N1CCN(CC(=O)O)Cc2cccc(n2)CN(CC(=O)O)CC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.42
FOLH1 Q04609 5/20 0.39
DRD3 P35462 3/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ADRA1A P35348 1/20 0.37
DRD2 P14416 1/20 0.37
NAMPT P43490 2/20 0.36
S1PR1 P21453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4367132 0.88 ALB (0.46) ALBFOLH1MEN1KMT2ADRD2
SCHEMBL4361026 0.82 SLC2A1 (0.41) ALBDRD3S1PR1
SCHEMBL4359589 0.81 SLC6A9 (0.39) ALBDRD3MAPTLMNA
SCHEMBL4372295 0.75 ALB (0.38) ALBFOLH1LMNATP53HPGD
SCHEMBL4369094 0.75 ALB (0.39) ALBFOLH1LMNATP53HPGD
SCHEMBL4366967 0.74 ALB (0.36) ALBFOLH1LMNA
SCHEMBL4371417 0.74 S1PR1 (0.41) ALBMAPTMEN1LMNAHPGD
SCHEMBL23723184 0.74 ALB (0.56) ALBFOLH1
SCHEMBL4359522 0.74 BACE1 (0.39) MAPTMEN1LMNAKMT2ANPSR1
SCHEMBL4362844 0.74 FOLH1 (0.38) ALBFOLH1MAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268810-B2 Lipophilic chelates and their use in imaging GUERBET (FR) 2012-09-18 US disclosed
US-20090214441-A1 Lipophilic Chelates and Their Use in Imaging GUERBET (FR) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090214441-A1 Lipophilic Chelates and Their Use in Imaging SLC40A1, TSPO, SLC47A2 ALB 1926/4885FOLH1 186/4885DRD3 1711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.