Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Propene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL6243344 | 1.00 | TSHR (0.73) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| Propene SCHEMBL11422813 | 1.00 | TSHR (0.73) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| Propene SCHEMBL28180423 | 0.98 | TSHR (0.70) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| Acrylic Acid SCHEMBL10429852 | 0.92 | TSHR (0.61) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| Butadiene SCHEMBL21933110 | 0.88 | TSHR (0.76) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| SCHEMBL28695678 | 0.88 | TSHR (0.76) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| SCHEMBL30955955 | 0.86 | TSHR (0.73) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| SCHEMBL28810412 | 0.86 | TSHR (0.73) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| Vinyl Chloride SCHEMBL28263245 | 0.86 | TSHR (0.73) | TSHRSMN1; SMN2TDP1CYP2D6POLB | |
| SCHEMBL27919091 | 0.86 | TSHR (0.73) | TSHRSMN1; SMN2TDP1CYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11322268-B2 | Method and device for disposing nuclear waste using deep geological repository | HARBIN QINGRUI SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2022-05-03 | — | — | US | claimed |
| CN-114208852-A | Compound suspending agent containing bacillus thuringiensis and preparation method and application thereof | 山东鲁抗生物农药有限责任公司 | 2022-03-22 | — | — | CN | claimed |
| CN-113845685-A | Manufacturing method of high-transparency anti-wear thermal deformation prevention PET packaging material | 深圳市星锦雅实业有限公司 | 2021-12-28 | — | — | CN | claimed |
| US-20190043629-A1 | METHOD AND DEVICE FOR DISPOSING NUCLEAR WASTE USING DEEP GEOLOGICAL REPOSITORY | HARBIN QINGRUI SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2019-02-07 | — | — | US | claimed |
| CN-1168807-C | Improved alkylbenzene sulfonate surfactant compositions | ������-�ʲ�����˾ | 2004-09-29 | — | — | CN | claimed |
| US-6774099-B1 | ALKYLARYLSULFONATE SURFACTANTS | THE PROCTER & GAMBLE COMPANY | 2004-08-10 | — | — | US | claimed |
| EP-1002030-B1 | DETERGENT COMPOSITIONS CONTAINING MIXTURES OF CRYSTALLINITY-DISRUPTED SURFACTANTS | PROCTER & GAMBLE (US) | 2003-05-21 | — | — | EP | claimed |
| CN-1353444-A | Shield disk and anti-explosion glass of plane coloured cathod ray tube and their adhesion method | LG ELECTRONICS INC (KR) | 2002-06-12 | — | — | CN | claimed |
| EP-1144573-A2 | DISHWASHING DETERGENT COMPOSITIONS CONTAINING MIXTURES OF CRYSTALLINITY-DISRUPTED SURFACTANTS | The Procter & Gamble Company (US) | 2001-10-17 | — | — | EP | claimed |
| US-6274540-B1 | ALKYLARYL SULFONATE MIXTURE | THE PROCTER & GAMBLE COMPANY | 2001-08-14 | — | — | US | claimed |
| CN-1270621-A | Improved alkylbenzene sulfonate surfactants | PROCTER & GAMBLE (US) | 2000-10-18 | — | — | CN | claimed |
| WO-2000043476-A2 | DISHWASHING DETERGENT COMPOSITIONS CONTAINING MIXTURES OF CRYSTALLINITY-DISRUPTED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-27 | — | — | WO | claimed |
| EP-1002030-A1 | DETERGENT COMPOSITIONS CONTAINING MIXTURES OF CRYSTALLINITY-DISRUPTED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999005243-A1 | DETERGENT COMPOSITIONS CONTAINING MIXTURES OF CRYSTALLINITY-DISRUPTED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-04 | — | — | WO | claimed |
| US-12624131-B2 | Methods for producing polyisoprene latex dispersions | BRIDGESTONE CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| EP-4347765-A1 | COMPOSITION | Unilever IP Holdings B.V. (NL) | 2024-04-10 | — | — | EP | disclosed |
| US-20230220124-A1 | METHODS FOR PRODUCING POLYISOPRENE LATEX DISPERSIONS | BRIDGESTONE CORPORATION (JP) | 2023-07-13 | — | — | US | disclosed |
| US-4268406-A | ANIONIC SURFACTANT, AMIDE, REDUCING AGENT, PROTEIN DENATURANT | THE PROCTER & GAMBLE COMPANY (US) | 1981-05-19 | — | — | US | disclosed |
| US-4181633-A | ANIONIC OR NONIONIC SURFACTANTS | COLGATE-PALMOLIVE COMPANY (US) | 1980-01-01 | — | — | US | disclosed |
| US-4051056-A | ALKYL SULFATE SURFACTANT, PERLITE, HYPOCHLORITE BLEACH, CLAY DISPERSANT | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624131-B2 | Methods for producing polyisoprene latex dispersions | DEGS1, ALG1, GEMIN5 | TSHR 4597/4885SMN1; SMN2 2390/4885TDP1 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.