SCHEMBL4609604

SCHEMBL4609604

Cc1cc(C(=O)c2ccccc2)ccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.57
NPC1 O15118 2/20 0.57
MITF O75030 1/20 0.57
LMNA P02545 1/20 0.57
PBRM1 Q86U86 1/20 0.56
TDP1 Q9NUW8 2/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAPT P10636 5/20 0.54
MAPK1 P28482 2/20 0.53
ALDH1A1 P00352 3/20 0.52
HTT P42858 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
HPGD P15428 1/20 0.50
CYP2C19 P33261 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SRD5A2 P31213 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436565 0.90 LMNA (0.56) POLBNPC1MITFLMNATDP1
SCHEMBL7195606 0.87 LMNA (0.54) POLBNPC1MITFLMNAPBRM1
SCHEMBL7194336 0.86 NPC1 (0.78) POLBNPC1MITFLMNAPBRM1
SCHEMBL2270464 0.85 MAPT (0.63) POLBNPC1MITFLMNAPBRM1
SCHEMBL12490393 0.85 HTT (0.70) POLBNPC1MITFLMNATDP1
SCHEMBL6234574 0.84 MAPK1 (0.50) POLBNPC1MITFLMNATDP1
SCHEMBL13783385 0.83 MAPT (0.66) POLBNPC1MITFLMNATDP1
SCHEMBL144914 0.82 PBRM1 (0.62) POLBNPC1LMNAPBRM1TDP1
SCHEMBL166495 0.82 SMN1; SMN2 (0.71) POLBNPC1MITFLMNAPBRM1
SCHEMBL10007010 0.82 SMN1; SMN2 (0.71) POLBNPC1MITFLMNAPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715595-B Synthesis method of 4-aminobenzophenone compound 台州学院 2025-04-18 CN disclosed
WO-2023211472-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-11-02 WO disclosed
CN-116715595-A Synthesis method of 4-aminobenzophenone compound 台州学院 2023-09-08 CN disclosed
EP-1059927-B1 CHEMICAL COMPOUNDS AND THEIR USE TO ELEVATE PYRUVATE DEHYDROGENASE ACTIVITY ASTRAZENECA AB (SE) 2008-07-30 EP disclosed
EP-0966424-B1 AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF LEO PHARMA AS (DK) 2004-06-23 EP disclosed
US-6623786-B2 Method for hydrogel surface treatment NOVARTIS AG (CH) 2003-09-23 US disclosed
US-6369273-B1 ARYL ALCOHOLS OR ESTERS FOR ELEVATION OF PYRUVATE DHYDROGENASE ASTRAZENECA AB (SE) 2002-04-09 US disclosed
EP-0617010-B1 Therapeutic compounds ASTRAZENECA AB (SE) 2002-01-09 EP disclosed
US-6313174-B1 FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) 2001-11-06 US disclosed
US-20010024697-A1 Method for hydrogel surface treatment and article formed therefrom BARON RICHARD CARLTON (US) 2001-09-27 US disclosed
EP-0966424-A1 AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1999-12-29 EP disclosed
WO-1999044618-A1 CHEMICAL COMPOUNDS AND THEIR USE TO ELEVATE PYRUVATE DEHYDROGENASE ACTIVITY ASTRAZENECA AB (SE) 1999-09-10 WO disclosed
US-5900432-A Therapeutic N-(4-benzoyl-2-methyl-phenyl)-3,3,3-trifluoro-2-hydroxy-2-methyl-propanamides ZENECA LIMITED (GB) 1999-05-04 US disclosed
WO-1999015917-A1 METHOD FOR HYDROGEL SURFACE TREATMENT AND ARTICLE FORMED THEREFROM NOVARTIS AG (CH) 1999-04-01 WO disclosed
WO-1998032730-A1 AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) 1998-07-30 WO disclosed
US-5482969-A Certain N(4-benzoyl-2-phenyl)-3- trifluoro-2-hydroxy-propanamide derivatives ZENECA LIMITED (GB) 1996-01-09 US disclosed
EP-0617010-A1 Therapeutic compounds ZENECA LIMITED (GB) 1994-09-28 EP disclosed
EP-0282978-B1 Surface acoustic wave convolver with dielectric film of high non-linear effect CANON KK (JP) 1993-12-01 EP disclosed
US-4882715-A Surface acoustic wave convolver with dielectric film of high non-linear effect CANON KABUSHIKI KAISHA (JP) 1989-11-21 US disclosed
EP-0282978-A2 Surface acoustic wave convolver with dielectric film of high non-linear effect CANON KABUSHIKI KAISHA (JP) 1988-09-21 EP disclosed