SCHEMBL4365735

SCHEMBL4365735

O=P(Cl)(ON1CCOCC1)ON1CCOCC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
CA12 O43570 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MAPT P10636 1/20 0.31
GAA P10253 1/20 0.31
ANPEP P15144 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819673 0.87 TSHR (0.34) MMP1MMP3MMP8CA12CA7
SCHEMBL11134004 0.86 MMP1 (0.35) MMP1MMP3MMP8CA12CA7
SCHEMBL9869777 0.84 TSHR (0.33) KMT2A
SCHEMBL8721057 0.82 KMT2A (0.43) MAPTGAAL3MBTL1MEN1KMT2A
SCHEMBL18426999 0.82 MMP1 (0.33) MMP1MMP3MMP8CA12CA7
SCHEMBL20473220 0.82 MMP1 (0.42) MMP1MMP3MMP8CA12CA7
SCHEMBL11417319 0.82 TSHR (0.34) MMP1MMP3MMP8CA12CA7
SCHEMBL28480518 0.81 SMN1; SMN2 (0.39) L3MBTL1
SCHEMBL4302310 0.80 MMP1 (0.38) MMP1MMP3MMP8CA12CA7
SCHEMBL31249535 0.80 LMNA (0.41) CA12CA7MAPTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118930580-A Preparation method of biomass phosphonamide flame retardant and application of biomass phosphonamide flame retardant in PA6/ABS alloy 禾欣可乐丽超纤皮(嘉兴)有限公司 2024-11-12 CN claimed
CN-118772150-A Midazolam-D3 and preparation method thereof 上海原思标物科技有限公司 2024-10-15 CN claimed
CN-117467255-A Polylactic acid composition with high flame retardance and crystallinity and preparation method thereof 江苏康辉新材料科技有限公司 2024-01-30 CN claimed
CN-117466936-A Bio-based flame-retardant nucleation additive for polyester and preparation method thereof 江苏康辉新材料科技有限公司 2024-01-30 CN claimed
CN-118772150-A Midazolam-D3 and preparation method thereof 上海原思标物科技有限公司 2024-10-15 CN disclosed
CN-117487327-A Flame-retardant low-dielectric-strength PBT composite material and preparation method thereof 江苏康辉新材料科技有限公司 2024-02-02 CN disclosed
CN-117487328-A Furanyl polyester composition with high barrier property and high crystallization property and preparation method thereof 江苏康辉新材料科技有限公司 2024-02-02 CN disclosed
CN-117467255-A Polylactic acid composition with high flame retardance and crystallinity and preparation method thereof 江苏康辉新材料科技有限公司 2024-01-30 CN disclosed
CN-117466936-A Bio-based flame-retardant nucleation additive for polyester and preparation method thereof 江苏康辉新材料科技有限公司 2024-01-30 CN disclosed
CN-117362941-A Refrigerant-resistant flame-retardant high-glass fiber reinforced PBT composite material with high crystallization temperature and preparation method thereof 江苏康辉新材料科技有限公司 2024-01-09 CN disclosed
CN-117327377-A Bio-based phosphonamide flame retardant nucleating agent reinforced PBT (polybutylene terephthalate) composition and preparation method thereof 江苏康辉新材料科技有限公司 2024-01-02 CN disclosed
US-7528127-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-05-05 US disclosed
US-20020077392-A1 Flame retardant polycarbonate resin composition CHEIL INDUSTRIES INC. (KR) 2002-06-20 US disclosed
EP-1207182-A1 Flame retardant thermoplastic resin composition Cheil Industries Inc. (KR) 2002-05-22 EP disclosed
EP-1201714-A1 Flame retardant thermoplastic resin composition Cheil Industries Inc. (KR) 2002-05-02 EP disclosed
EP-1183243-A1 SHORT-ACTING BENZODIAZEPINES GLAXO GROUP LIMITED (GB) 2002-03-06 EP disclosed
WO-2000069836-A1 SHORT-ACTING BENZODIAZEPINES GLAXO GROUP LIMITED (GB) 2000-11-23 WO disclosed
EP-0033974-B1 BENZODIAZEPINE DERIVATIVES, INTERMEDIATES AND PROCESSES FOR PREPARING THEM, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-09-28 EP disclosed
US-4374773-A ALDOSTERONE ANTAGONIST HOFFMANN-LA ROCHE INC. (US) 1983-02-22 US disclosed
EP-0033974-A1 Benzodiazepine derivatives, intermediates and processes for preparing them, their use and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-08-19 EP disclosed